Trintellix ( vortioxetine ) is a prescription drug used to treat major depressive disorder in adults. Pae C-U, Wang S_M, Han C, et al.Compare Trintellix alternatives | Selective serotonin reuptake inhibitors | Serotonin norepinephrine reuptake inhibitors | Atypical antidepressants | Tricyclic antidepressants | Monoamine oxidase inhibitors | Natural alternatives | How to switch meds. Trintellix (vortioxetine) Medical News Today.Trintellix (Vortioxetine) & Weight Gain or Weight Loss? Mental Health Daily.Trintellix (vortioxetine) Cardinal Health.Trintellix is classified as a miscellaneous antidepressant, although some classify it as an SSRI (selective serotonin reuptake inhibitor) and a serotonin receptor modulator. It aims to reduce depressive symptoms and prevent them from returning. Because it acts as an antagonist/agonist and partial agonist, this is thought to enhance its antidepressant effects and prevent desensitization of the presynaptic neuron. Trintellix is different from other antidepressants currently on the market because of its direct effects on various serotonin receptors as well as inhibiting serotonin reuptake. It also has effects on other serotonin receptors, such as 5-HT1A (agonist effects) and 5-HT3 (antagonist effects), although experts are not sure if this action contributes to vortioxetine’s antidepressant effect. How does Trintellix work?Įxperts aren’t sure exactly how Trintellix works but it is thought to be due to its increasing levels of a neurotransmitter, called serotonin in the brain. You can choose whether you take Trintellix in the morning or at night however, if you find Trintellix interferes with your sleep or makes you restless or energized, try taking it in the morning. Trintellix only needs to be taken once a day. Trintellix was previously called Brintellix but the name was changed in 2016 after confusion in the marketplace between Brintellix and another medicine. Trintellix (vortioxetine) is an antidepressant that is usually used to treat the symptoms of major depressive disorder. The authors concluded that because of the limited number of trials, more trials are needed before Trintellix is given routinely for GAD.
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